Gen Z’s “Supplement Stacking” Habit: All-in-One Formulations Become the New OEM Trend

 “Supplement stacking” is reshaping the dietary supplement landscape. From over 2.8 million #supplements videos on TikTok to daily routines where consumers combine multiple ingredients for combined health benefits, this trend has moved from influencer culture to mainstream demand.

1. What is supplement stacking?

Supplement stacking means consumers intentionally combine several synergistic ingredients to achieve specific wellness goals – such as stress management, energy boost, recovery support – rather than relying solely on a single multivitamin. The focus has shifted from “more intake” to “precision nutrition,” valuing synergy between ingredients. Social media has greatly accelerated this movement; dietary supplement sales on TikTok Shop surpassed USD 1 billion in 2025 alone.

2. From “customised stacks” to “allinone formulas”

Under the supplement stacking wave, welldesigned allinone formulas are seeing explosive growth. For consumers, buying many singleingredient products is timeconsuming and costly. For brands, a single formula that addresses several benefits at once offers both cost efficiency and clear communication. Brands are now blending multiple functional ingredients into one product, providing complete nutritional support in a simpler way. This trend is especially strong in beautyfromwithin products, where multitarget synergistic formulas are replacing singleingredient items (e.g., antiageing, antihair loss). Functional foods are also moving toward streamlined composite formulas, making daily supplementation easier and reducing the hassle of taking multiple separate products.

3. OEM innovations for allinone formulas across four dosage forms

Implementing complex formulas requires solutions for multiingredient compatibility, stability, and dosage form suitability.

Softgels – Liquidfilled multilayer technology can separate oilsoluble and watersoluble components within one softgel, ideal for composite formulas. Softgels remain a top choice (second only to powders in growth).

Hard capsules – Can accommodate both powders and minitablets/pellets, suitable for multitarget formulas (e.g., Maca + Ashwagandha blends already in production).

Tablets – Mature compression technology; multilayer tablets enable timesequenced release of different actives. Although tablet growth has slowed, new formats like chewables and effervescent tablets are gaining favour among young consumers who want a “nonpill” experience.

Powders – The fastestgrowing format (+8% YoY) and the most flexible carrier for complex formulas. Powders can hold many active ingredients without capsule shell limitations, can be flavoured naturally, and are a top choice for beautyfromwithin and sports nutrition.

4. How Gen Z habits impact the OEM industry

Gen Z values lifestyleoriented consumption – they want supplements that fit seamlessly into their daily routines. At the same time, increased awareness of bioavailability is driving OEMs to adopt pharmaceutical technologies that improve absorption. The rapid viral nature of TikTok requires OEMs to react quickly to trending ingredients, compressing lead times from raw material sourcing to finished product launch.

5. Opportunities for private label/OEM clients

For brands, the allinone formula trend opens huge opportunities. We suggest three strategic directions:

Focus on niche demographics and develop synergistic formulas (e.g., beautyfromwithin + antiglycation, sleep + mood support).

Partner with flexible OEM manufacturers that can respond quickly to market trends and differentiate your brand.

Pay attention to ingredient compatibility and bioavailability during formula design to keep your products aligned with evolving consumer preferences.

As a source manufacturer with 18 years of experience, we specialise in OEM/ODM services for softgels, hard capsules, tablets, and powders. We have extensive expertise in developing multiingredient compatible formulas and provide onestop solutions to help brands capture the Gen Z “supplement stacking” blue ocean.